Contraindicated (1)pentobarbital will decrease the extent or effect of cariprazine by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated. CYP3A4 is chargeable for the formation and elimination of cariprazine's Energetic metabolites.
pentobarbital will minimize the level or impact of ramelteon by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Small/Significance Unknown.
pentobarbital will minimize the level or influence of bosentan by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Slight/Significance Mysterious.
pentobarbital will decrease the extent or impact of estrogens esterified by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Keep track of.
pentobarbital will minimize the extent or effect of voriconazole by affecting hepatic enzyme CYP2C9/10 metabolism. Insignificant/Importance Not known.
pentobarbital will decrease the level or influence of diazepam buccal by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Check. Sturdy or average CYP3A4 inducers may perhaps enhance amount of diazepam elimination; hence, efficacy of diazepam might be lowered.
pentobarbital will decrease the level or influence of eplerenone by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Minimal/Importance Mysterious.
pentobarbital will lessen the extent or result of copyright topical by impacting hepatic enzyme CYP2B6 metabolism. Minor/Importance Mysterious.
pentobarbital will decrease the extent or impact of vinorelbine by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Slight/Importance Unknown.
pentobarbital will lessen the extent or influence of rabeprazole by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Slight/Significance Unidentified.
Workout caution when a barbiturate is administered to the nursing female; little quantities of barbiturates are excreted inside the milk
pentobarbital will lower the extent or impact of ethinylestradiol by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Steer clear of or Use Alternate Drug. The efficacy of hormonal contraceptives could possibly be lessened. Usage of a nonhormonal contraceptive is recommended.
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Pentobarbital interacts with a number of big classes of prescription drugs and needs close checking to take care of therapeutic drug stages. As a category, barbiturates induce hepatic microsomal enzymes, which click here increase the price of metabolism of other medications metabolized by these hepatic enzymes.